Systems Genomics

We are a dynamic, transnational research lab with nodes at the Baker Heart and Diabetes Institute (Melbourne, AU) and the Department of Public Health and Primary Care and Heart and Lung Research Institute at the University of Cambridge (UK). The lab is the home of the Cambridge Baker Systems Genomics Initiative, a partnership bringing together data science expertise and massive multi-omics datasets, and is also part of Health Data Research UK.

The Inouye Lab aims to alleviate the burden of disease using its interdisciplinary strengths in statistics, computation and bioscience to leverage the latest genomic/biomolecular technologies.

We focus on research questions in cardiovascular and respiratory disease but maintain broad interests, including:

• • design, application and cataloging of polygenic scores (e.g. coronary artery disease, or PGS Catalog)

  • methods and applications for integrative analysis of genomic and systems-level biomolecular data (e.g. GlycA)

  • host interactions of microbiota/pathogens and their role in disease (e.g. asthma)

  • approaches for environment-friendly bioinformatics and HPC/cloud computing (e.g. Green Algorithms Project)

For more information see our Publications.